TSPAN2

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Tetraspanin 2
Identifiers
Symbol(s) TSPAN2; 6330415F13Rik; FLJ12082; RP4-666F24.2; TSN2; TSPAN-2
External IDs MGI: 1917997 HomoloGene: 21169
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10100 70747
Ensembl ENSG00000134198 ENSMUSG00000027858
Uniprot O60636 Q8C0C9
Refseq NM_005725 (mRNA)
NP_005716 (protein)		 NM_027533 (mRNA)
NP_081809 (protein)
Location Chr 1: 115.39 - 115.43 Mb Chr 3: 102.86 - 102.9 Mb
Pubmed search [1] [2]

Tetraspanin 2, also known as TSPAN2, is a human gene.[1]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.[1]

[edit] References

  1. ^ a b Entrez Gene: TSPAN2 tetraspanin 2.

[edit] Further reading

  • Hemler ME (2002). "Specific tetraspanin functions.". J. Cell Biol. 155 (7): 1103-7. doi:10.1083/jcb.200108061. PMID 11756464. 
  • Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye.". J. Cell. Sci. 114 (Pt 23): 4143-51. PMID 11739647. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Todd SC, Doctor VS, Levy S (1998). "Sequences and expression of six new members of the tetraspanin/TM4SF family.". Biochim. Biophys. Acta 1399 (1): 101-4. PMID 9714763. 
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