TSPAN13

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Tetraspanin 13
Identifiers
Symbol(s) TSPAN13; FLJ22934; NET-6; TM4SF13
External IDs MGI: 1913359 HomoloGene: 8671
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 27075 66109
Ensembl ENSG00000106537 ENSMUSG00000020577
Uniprot O95857 Q9D8C2
Refseq NM_014399 (mRNA)
NP_055214 (protein)		 NM_025359 (mRNA)
NP_079635 (protein)
Location Chr 7: 16.76 - 16.79 Mb Chr 12: 36.52 - 36.55 Mb
Pubmed search [1] [2]

Tetraspanin 13, also known as TSPAN13, is a human gene.[1]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.[1]

[edit] References

  1. ^ a b Entrez Gene: TSPAN13 tetraspanin 13.

[edit] Further reading

  • Böhme E, Graf H, Schultz G (1978). "Effects of sodium nitroprusside and other smooth muscle relaxants on cyclic GMP formation in smooth muscle and platelets.". Advances in cyclic nucleotide research 9: 131-43. PMID 27075. 
  • Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye.". J. Cell. Sci. 114 (Pt 23): 4143-51. PMID 11739647. 
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548. 
  • Serru V, Dessen P, Boucheix C, Rubinstein E (2000). "Sequence and expression of seven new tetraspans.". Biochim. Biophys. Acta 1478 (1): 159-63. PMID 10719184. 
  • Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543-8. doi:10.1073/pnas.160270997. PMID 10931946. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Huang H, Groth J, Sossey-Alaoui K, et al. (2005). "Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors.". Clin. Cancer Res. 11 (12): 4357-64. doi:10.1158/1078-0432.CCR-04-2107. PMID 15958618. 
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743. 
  • Moroz MA, Serganova I, Zanzonico P, et al. (2007). "Imaging hNET reporter gene expression with 124I-MIBG.". J. Nucl. Med. 48 (5): 827-36. doi:10.2967/jnumed.106.037812. PMID 17475971. 
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