Tryptophan-phenylpyruvate transaminase

From Wikipedia, the free encyclopedia

In enzymology, a tryptophan-phenylpyruvate transaminase (EC 2.6.1.28) is an enzyme that catalyzes the chemical reaction

L-tryptophan + phenylpyruvate (indol-3-yl)pyruvate + L-phenylalanine

Thus, the two substrates of this enzyme are L-tryptophan and phenylpyruvate, whereas its two products are (indol-3-yl)pyruvate and L-phenylalanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-tryptophan:phenylpyruvate aminotransferase. This enzyme is also called L-tryptophan-alpha-ketoisocaproate aminotransferase.

[edit] References

• IUBMB entry for 2.6.1.28
• BRENDA references for 2.6.1.28 (Recommended.)
• PubMed references for 2.6.1.28
• PubMed Central references for 2.6.1.28
• Google Scholar references for 2.6.1.28
• Koide Y, Honma M and Shimomura T (1980). "L-Tryptophan-alpha-ketoisocaproate aminotransferase from Pseudomonas sp". Agric. Biol. Chem. 44: 2013–2019. 
• Sukanya NK, Vaidyanathan CS (1964). "Aminotransferases of Agrobacterium tumefaciens. Transamination between tryptophan and phenylpyruvate". Biochem. J. 92: 594–8. PMID 5837443. 

[edit] External links

The CAS registry number for this enzyme class is 37277-87-5.

• IUBMB entry for 2.6.1.28

• KEGG entry for 2.6.1.28

• BRENDA entry for 2.6.1.28

• NiceZyme view of 2.6.1.28

• EC2PDB: PDB structures for 2.6.1.28

• PRIAM entry for 2.6.1.28

• PUMA2 entry for 2.6.1.28

• IntEnz: Integrated Enzyme entry for 2.6.1.28

• MetaCyc entry for 2.6.1.28

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047299: tryptophan-phenylpyruvate transaminase

• AMIGO entry for GO code 0047299: tryptophan-phenylpyruvate transaminase