Tropane
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| Tropane[1] | |
|---|---|
 |
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| IUPAC name | 8-Methyl-8-azabicyclo[3.2.1]octane |
| Other names | 2,3-Dihydro-8-methylnortropidine |
| Identifiers | |
| CAS number | [529-17-9] |
| PubChem | |
| SMILES | CN1C2CCC1CCC2 |
| Properties | |
| Molecular formula | C8H15N |
| Molar mass | 125.211 g/mol |
| Density | 0.9259 at 15 °C |
| Boiling point |
163-169 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Tropane is a nitrogenous bicyclic organic compound. It is mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine. Both alkaloids contain tropinone from which tropane is a derivate. Tropane alkaloids occur in plants of the families Erythroxylaceae (including coca) and Solanaceae (including mandrake, henbane, deadly nightshade, datura, potato, tomato) .[2][3]
8-Azabicyclo[3.2.1]octane (tropane without the 8-methyl group) is known as nortropane or nor-tropane.
Condensation piperidine and pyrrolidine produce tropane.
[edit] See also
[edit] References
- ^ Merck Index, 11th Edition, 9689.
- ^ Atropine content of plants. USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases. [Online Database] National Germplasm Resources Laboratory, Beltsville, Maryland. Retrieved on July 25, 2005.
- ^ Cocaine content of plants. USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases. [Online Database] National Germplasm Resources Laboratory, Beltsville, Maryland. Retrieved on July 25, 2005.
[edit] External links
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