Triphosphoribosyl-dephospho-CoA synthase
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In enzymology, a triphosphoribosyl-dephospho-CoA synthase (EC 2.7.8.25) is an enzyme that catalyzes the chemical reaction
- ATP + 3-dephospho-CoA
2'-(5"-triphosphoribosyl)-3'-dephospho-CoA + adenine
Thus, the two substrates of this enzyme are ATP and 3-dephospho-CoA, whereas its two products are [[2'-(5-triphosphoribosyl)-3'-dephospho-CoA]] and adenine.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is ATP:3-dephospho-CoA 5"-triphosphoribosyltransferase. Other names in common use include 2'-(5"-triphosphoribosyl)-3-dephospho-CoA synthase, ATP:dephospho-CoA 5-triphosphoribosyl transferase, and CitG. This enzyme participates in two-component system - general.
[edit] References
- IUBMB entry for 2.7.8.25
- BRENDA references for 2.7.8.25 (Recommended.)
- PubMed references for 2.7.8.25
- PubMed Central references for 2.7.8.25
- Google Scholar references for 2.7.8.25
- Schneider K, Dimroth P, Bott M (2000). "Biosynthesis of the prosthetic group of citrate lyase". Biochemistry. 39: 9438–50. doi:. PMID 10924139.
- Schneider K, Dimroth P, Bott M (2000). "Identification of triphosphoribosyl-dephospho-CoA as precursor of the citrate lyase prosthetic group". FEBS. Lett. 483: 165–8. doi:. PMID 11042274.
[edit] External links
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- The CAS registry number for this enzyme class is 313345-38-9.
[edit] Gene Ontology (GO) codes
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