TRIM9

From Wikipedia, the free encyclopedia


Tripartite motif-containing 9
PDB rendering based on 2db8.
Available structures: 2db8
Identifiers
Symbol(s) TRIM9; KIAA0282; RNF91; SPRING
External IDs OMIM: 606555 MGI2137354 HomoloGene9045
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 114088 94090
Ensembl ENSG00000100505 ENSMUSG00000021071
Uniprot Q9C026 Q3TR28
Refseq NM_015163 (mRNA)
NP_055978 (protein)
NM_053167 (mRNA)
NP_444397 (protein)
Location Chr 14: 50.51 - 50.63 Mb Chr 12: 71.17 - 71.27 Mb
Pubmed search [1] [2]

Tripartite motif-containing 9, also known as TRIM9, is a human gene.[1]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[1]

[edit] References

[edit] Further reading

  • Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954. 
  • Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317-20. PMID 1602151. 
  • Ohara O, Nagase T, Ishikawa K, et al. (1997). "Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.". DNA Res. 4 (1): 53-9. PMID 9179496. 
  • Reymond A, Meroni G, Fantozzi A, et al. (2001). "The tripartite motif family identifies cell compartments.". EMBO J. 20 (9): 2140-51. doi:10.1093/emboj/20.9.2140. PMID 11331580. 
  • Li Y, Chin LS, Weigel C, Li L (2001). "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis.". J. Biol. Chem. 276 (44): 40824-33. doi:10.1074/jbc.M106141200. PMID 11524423. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.