Trehalose O-mycolyltransferase

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In enzymology, a trehalose O-mycolyltransferase (EC 2.3.1.122) is an enzyme that catalyzes the chemical reaction

2 alpha,alpha-trehalose 6-mycolate alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate

Hence, this enzyme has one substrate, alpha,alpha'-trehalose 6-mycolate, and two products, alpha,alpha-trehalose and alpha,alpha'-trehalose 6,6'-bismycolate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is alpha,alpha-trehalose-6-mycolate:alpha,alpha-trehalose-6-mycolate 6'-mycolyltransferase. Other names in common use include alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose, mycolyltransferase, alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate, and 6'-mycolyltransferase.

[edit] References

• IUBMB entry for 2.3.1.122
• BRENDA references for 2.3.1.122 (Recommended.)
• PubMed references for 2.3.1.122
• PubMed Central references for 2.3.1.122
• Google Scholar references for 2.3.1.122
• Sathyamoorthy N, Takayama K (1987). "Purification and characterization of a novel mycolic acid exchange enzyme from Mycobacterium smegmatis". J. Biol. Chem. 262: 13417–23. PMID 3654621. 

[edit] External links

The CAS registry number for this enzyme class is 111694-11-2.

• IUBMB entry for 2.3.1.122

• KEGG entry for 2.3.1.122

• BRENDA entry for 2.3.1.122

• NiceZyme view of 2.3.1.122

• EC2PDB: PDB structures for 2.3.1.122

• PRIAM entry for 2.3.1.122

• PUMA2 entry for 2.3.1.122

• IntEnz: Integrated Enzyme entry for 2.3.1.122

• MetaCyc entry for 2.3.1.122

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050348: trehalose O-mycolyltransferase

• AMIGO entry for GO code 0050348: trehalose O-mycolyltransferase