Trehalose-phosphatase

From Wikipedia, the free encyclopedia

In enzymology, a trehalose-phosphatase (EC 3.1.3.12) is an enzyme that catalyzes the chemical reaction

alpha,alpha-trehalose 6-phosphate + H₂O alpha,alpha-trehalose + phosphate

Thus, the two substrates of this enzyme are alpha,alpha'-trehalose 6-phosphate and H₂O, whereas its two products are alpha,alpha-trehalose and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is alpha,alpha-trehalose-6-phosphate phosphohydrolase. Other names in common use include trehalose 6-phosphatase, trehalose 6-phosphate phosphatase, and trehalose-6-phosphate phosphohydrolase. This enzyme participates in starch and sucrose metabolism.

[edit] References

• IUBMB entry for 3.1.3.12
• BRENDA references for 3.1.3.12 (Recommended.)
• PubMed references for 3.1.3.12
• PubMed Central references for 3.1.3.12
• Google Scholar references for 3.1.3.12
• CABIB E, LELOIR LF (1958). "The biosynthesis of trehalose phosphate". J. Biol. Chem. 231: 259–75. PMID 13538966. 
• CANDY DJ, KILBY BA (1961). "The biosynthesis of trehalose in the locust fat body". Biochem. J. 78: 531–6. PMID 13690400. 

[edit] External links

The CAS registry number for this enzyme class is 9025-72-3.

• IUBMB entry for 3.1.3.12

• KEGG entry for 3.1.3.12

• BRENDA entry for 3.1.3.12

• NiceZyme view of 3.1.3.12

• EC2PDB: PDB structures for 3.1.3.12

• PRIAM entry for 3.1.3.12

• PUMA2 entry for 3.1.3.12

• IntEnz: Integrated Enzyme entry for 3.1.3.12

• MetaCyc entry for 3.1.3.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004805: trehalose-phosphatase

• AMIGO entry for GO code 0004805: trehalose-phosphatase