Trans-splicing
From Wikipedia, the free encyclopedia
Trans-splicing is a special form of RNA processing in eukaryotes where exons from two different primary RNA transcripts are joined end to end and ligated.
In contrast "normal" (cis-)splicing processes a single molecule. That is, trans-splicing results in an RNA transcript that came from multiple RNA polymerases on the genome.
[edit] References
- Dixon RJ, Eperon IC, Samani NJ (2007). "Complementary intron sequence motifs associated with human exon repetition: a role for intragenic, inter-transcript interactions in gene expression". Bioinformatics 23 (2): 150-5. doi:. PMID 17105720.
- Yang Y, Walsh CE (2005). "Spliceosome-mediated RNA trans-splicing". Mol. Ther. 12 (6): 1006-12. doi:. PMID 16226059.
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