Talk:Transcriptome
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[edit] From PNA/Biology
- Transcriptome -- this page is just a skeleton with lots of headings and little else. And while the word is a bit dubious, the other xxxome-pages (expressome!? regulatome? give me a break) referenced smack way too much of creative word games. In addition, I don't think the definition is the only one possible; I'm fairly sure transcriptome is used to refer to the set of transcribed sequences, i.e. all the different transcripts produced from a genome. Ketil 2004-11-04
- Transcriptome is a legitimate, albeit annoying, term in biology and has a place in comparative studies of states (e.g. cancerous vs. 'normal' tissue) and other comparative measures. It's one of those 'omics explosion' terms. Courtland 2005-01-31
- I spent some time collapsing the lists of links on the several omics pages by introducing the List of omics topics in biology page and cleaning up the several pages it references. I do wish the person(s) who had originally put these up had not been in such a hurry to dash them up then walk away ... or so it seems from my perspective. At the very least they should have been put in as stubbies ... hey, that's not a bad middle ground really. What do you think? Courtland 2005-01-31 (almost 02-01)
[edit] Not just mRNA
I think the term "transcriptome" refers to all RNA transcripts, not just messenger RNA. Searching for the term on Pubmed leads to several articles that specifically mention trying to figure what's all that non-coding RNA doing. See also Affymetrix's page on the topic at http://www.affymetrix.com/transcriptome/index.affx, and I guess they should know since that's why their products exist (tracking expression levels). In fact, reading the first paragraph it sounds like the original author intended to mean all RNA transcripts. The last paragraph directly references an article where antisense transcripts are part of the transcriptome. Unless someone objects in the next few days, I'll edit the page to correct this. -Lp 70.81.26.125 16:02, 1 September 2007 (UTC)
