TPBG

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Trophoblast glycoprotein
Identifiers
Symbol(s) TPBG; 5T4; 5T4-AG; M6P1
External IDs OMIM: 190920 MGI: 1341264 HomoloGene: 4859
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 7162 21983
Ensembl ENSG00000146242 ENSMUSG00000035274
Uniprot Q13641 Q3UPI2
Refseq NM_006670 (mRNA)
NP_006661 (protein)		 NM_011627 (mRNA)
NP_035757 (protein)
Location Chr 6: 83.13 - 83.14 Mb Chr 9: 85.64 - 85.64 Mb
Pubmed search [1] [2]

Trophoblast glycoprotein, also known as TPBG, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: TPBG trophoblast glycoprotein.

[edit] Further reading

  • Carsberg CJ, Myers KA, Evans GS, et al. (1995). "Metastasis-associated 5T4 oncofoetal antigen is concentrated at microvillus projections of the plasma membrane.". J. Cell. Sci. 108 ( Pt 8): 2905-16. PMID 7593330. 
  • Myers KA, Rahi-Saund V, Davison MD, et al. (1994). "Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats.". J. Biol. Chem. 269 (12): 9319-24. PMID 8132670. 
  • Carsberg CJ, Myers KA, Stern PL (1996). "Metastasis-associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells.". Int. J. Cancer 68 (1): 84-92. doi:10.1002/(SICI)1097-0215(19960927)68:1<84::AID-IJC15>3.0.CO;2-6. PMID 8895545. 
  • King KW, Sheppard FC, Westwater C, et al. (1999). "Organisation of the mouse and human 5T4 oncofoetal leucine-rich glycoprotein genes and expression in foetal and adult murine tissues.". Biochim. Biophys. Acta 1445 (3): 257-70. PMID 10366710. 
  • Awan A, Lucic MR, Shaw DM, et al. (2002). "5T4 interacts with TIP-2/GIPC, a PDZ protein, with implications for metastasis.". Biochem. Biophys. Res. Commun. 290 (3): 1030-6. doi:10.1006/bbrc.2001.6288. PMID 11798178. 
  • Shaw DM, Woods AM, Myers KA, et al. (2002). "Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen.". Biochem. J. 363 (Pt 1): 137-45. PMID 11903056. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Mulryan K, Ryan MG, Myers KA, et al. (2003). "Attenuated recombinant vaccinia virus expressing oncofetal antigen (tumor-associated antigen) 5T4 induces active therapy of established tumors.". Mol. Cancer Ther. 1 (12): 1129-37. PMID 12481437. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743. 
  • Ward CM, Eastham AM, Stern PL (2006). "Cell surface 5T4 antigen is transiently upregulated during early human embryonic stem cell differentiation: effect of 5T4 phenotype on neural lineage formation.". Exp. Cell Res. 312 (10): 1713-26. doi:10.1016/j.yexcr.2006.02.006. PMID 16616918. 
  • Smyth LJ, Elkord E, Taher TE, et al. (2006). "CD8 T-cell recognition of human 5T4 oncofetal antigen.". Int. J. Cancer 119 (7): 1638-47. doi:10.1002/ijc.22018. PMID 16646078. 
  • Okazaki S, Sekizawa A, Purwosunu Y, et al. (2007). "Placenta-derived, cellular messenger RNA expression in the maternal blood of preeclamptic women.". Obstetrics and gynecology 110 (5): 1130-6. doi:10.1097/01.AOG.0000286761.11436.67. PMID 17978129. 
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