Tombusvirus internal replication element (IRE)

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Tombusvirus internal replication element (IRE)
Template:Abbreviation
Type: Cis-reg;
2° structure: Predicted; PFOLD;
Seed alignment: PubMed
Avg length: 88.7 nucleotides
Avg identity: 85%

In virology, the tombusvirus internal replication element (IRE) is a segment of RNA located within the region coding for p92 polymerase. This element is essential for viral replication; specifically, it is thought to be required at an early stage of replication, such as template recruitment and/or replicase complex assembly.[1]

[edit] References

  1. ^ Monkewich, S; Lin HX, Fabian MR, Xu W, Na H, Ray D, Chernysheva OA, Nagy PD, White KA (2005). "The p92 Polymerase Coding Region Contains an Internal RNA Element Required at an Early Step in Tombusvirus Genome Replication". J Virol 79: 4848–4858. doi:10.1128/JVI.79.8.4848-4858.2005. PMID 15795270. 

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