Tocopherol O-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a tocopherol O-methyltransferase (EC 2.1.1.95) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + gamma-tocopherol S-adenosyl-L-homocysteine + alpha-tocopherol

Thus, the two substrates of this enzyme are S-adenosyl methionine and gamma-tocopherol, whereas its two products are S-adenosylhomocysteine and alpha-tocopherol.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase. This enzyme is also called gamma-tocopherol methyltransferase. This enzyme participates in biosynthesis of steroids.

[edit] References

• IUBMB entry for 2.1.1.95
• BRENDA references for 2.1.1.95 (Recommended.)
• PubMed references for 2.1.1.95
• PubMed Central references for 2.1.1.95
• Google Scholar references for 2.1.1.95
• Camara B and D'Harlingue A (1985). "Demonstration and solubilization of S-adenosylmethionine - gamma-tocopherol methyltransferase from capsicum chromoplasts". Plant Cell Rep. 4: 31–32. doi:10.1007/BF00285499. 

[edit] External links

The CAS registry number for this enzyme class is 84788-82-9.

• IUBMB entry for 2.1.1.95

• KEGG entry for 2.1.1.95

• BRENDA entry for 2.1.1.95

• NiceZyme view of 2.1.1.95

• EC2PDB: PDB structures for 2.1.1.95

• PRIAM entry for 2.1.1.95

• PUMA2 entry for 2.1.1.95

• IntEnz: Integrated Enzyme entry for 2.1.1.95

• MetaCyc entry for 2.1.1.95

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050342: tocopherol O-methyltransferase

• AMIGO entry for GO code 0050342: tocopherol O-methyltransferase