TNS4

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Tensin 4
Identifiers
Symbol(s) TNS4; CTEN; FLJ14950; PP14434
External IDs OMIM: 608385 MGI: 2144377 HomoloGene: 13147
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 84951 217169
Ensembl ENSG00000131746 ENSMUSG00000017607
Uniprot Q8IZW8 Q8BZ33
Refseq NM_032865 (mRNA)
NP_116254 (protein)		 NM_172564 (mRNA)
NP_766152 (protein)
Location Chr 17: 35.89 - 35.91 Mb Chr 11: 98.88 - 98.91 Mb
Pubmed search [1] [2]

Tensin 4, also known as TNS4, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: TNS4 tensin 4.

[edit] Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548. 
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. PMID 10737800. 
  • Lo SH, Lo TB (2002). "Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer.". Cancer Res. 62 (15): 4217–21. PMID 12154022. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Sasaki H, Moriyama S, Mizuno K, et al. (2003). "Cten mRNA expression was correlated with tumor progression in lung cancers.". Lung Cancer 40 (2): 151–5. PMID 12711115. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Sasaki H, Yukiue H, Kobayashi Y, et al. (2004). "Cten mRNA expression is correlated with tumor progression in thymoma.". Tumour Biol. 24 (5): 271–4. doi:10.1159/000076141. PMID 15001839. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression.". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMID 15498874. 
  • Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.". Mol. Cell Proteomics 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465. 
  • Lo SS, Lo SH, Lo SH (2005). "Cleavage of cten by caspase-3 during apoptosis.". Oncogene 24 (26): 4311–4. doi:10.1038/sj.onc.1208571. PMID 15806167. 
  • Liao YC, Si L, deVere White RW, Lo SH (2007). "The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1.". J. Cell Biol. 176 (1): 43–9. doi:10.1083/jcb.200608015. PMID 17190795. 
  • Katz M, Amit I, Citri A, et al. (2007). "A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.". Nat. Cell Biol. 9 (8): 961–9. doi:10.1038/ncb1622. PMID 17643115. 
  • Mouneimne G, Brugge JS (2007). "Tensins: a new switch in cell migration.". Dev. Cell 13 (3): 317–9. doi:10.1016/j.devcel.2007.08.010. PMID 17765673. 
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