TNPO3

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Transportin 3
Identifiers
Symbol(s) TNPO3; IPO12; MTR10A; TRN-SR; TRN-SR2; TRNSR
External IDs OMIM: 610032 MGI: 1196412 HomoloGene: 40848
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 23534 320938
Ensembl ENSG00000064419 ENSMUSG00000012535
Uniprot Q9Y5L0 Q3UL39
Refseq NM_012470 (mRNA)
NP_036602 (protein)		 NM_177296 (mRNA)
NP_796270 (protein)
Location Chr 7: 128.38 - 128.48 Mb Chr 6: 29.49 - 29.56 Mb
Pubmed search [1] [2]

Transportin 3, also known as TNPO3, is a human gene.[1]

TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins, which are essential precursor-mRNA splicing factors (Kataoka et al., 1999).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: TNPO3 transportin 3.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Kataoka N, Bachorik JL, Dreyfuss G (1999). "Transportin-SR, a nuclear import receptor for SR proteins.". J. Cell Biol. 145 (6): 1145-52. PMID 10366588. 
  • Lai MC, Lin RI, Huang SY, et al. (2000). "A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins.". J. Biol. Chem. 275 (11): 7950-7. PMID 10713112. 
  • Lai MC, Lin RI, Tarn WY (2001). "Transportin-SR2 mediates nuclear import of phosphorylated SR proteins.". Proc. Natl. Acad. Sci. U.S.A. 98 (18): 10154-9. doi:10.1073/pnas.181354098. PMID 11517331. 
  • Allemand E, Dokudovskaya S, Bordonné R, Tazi J (2003). "A conserved Drosophila transportin-serine/arginine-rich (SR) protein permits nuclear import of Drosophila SR protein splicing factors and their antagonist repressor splicing factor 1.". Mol. Biol. Cell 13 (7): 2436-47. doi:10.1091/mbc.E02-02-0102. PMID 12134081. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Tsang HT, Connell JW, Brown SE, et al. (2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.". Genomics 88 (3): 333-46. doi:10.1016/j.ygeno.2006.04.003. PMID 16730941. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
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