TNKS1BP1

From Wikipedia, the free encyclopedia

Tankyrase 1 binding protein 1, 182kDa

Identifiers

TNKS1BP1; FLJ45975; KIAA1741; TAB182

External IDs

OMIM: 607104 MGI: 2446193 HomoloGene: 14117

Gene ontology
Molecular Function:	• enzyme binding • ankyrin binding
Cellular Component:	• nucleus • chromosome • nuclear telomeric heterochromatin • cytoplasm
Biological Process:	• telomere maintenance via telomerase

Orthologs

Human

Mouse

Refseq

NM_033396 (mRNA)
NP_203754 (protein)

XM_001001384 (mRNA)
XP_001001384 (protein)

Location

Chr 11: 56.82 - 56.85 Mb

Chr 2: 84.86 - 84.87 Mb

Pubmed search

[1]

[2]

Tankyrase 1 binding protein 1, 182kDa, also known as TNKS1BP1, is a human gene.^[1]

[edit] References

^ Entrez Gene: TNKS1BP1 tankyrase 1 binding protein 1, 182kDa.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. PMID 12168954.
Nagase T, Kikuno R, Hattori A, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (6): 347–55. PMID 11214970.
Seimiya H, Smith S (2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182).". J. Biol. Chem. 277 (16): 14116–26. doi:10.1074/jbc.M112266200. PMID 11854288.
Sbodio JI, Chi NW (2002). "Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner.". J. Biol. Chem. 277 (35): 31887–92. doi:10.1074/jbc.M203916200. PMID 12080061.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Jikuya H, Takano J, Kikuno R, et al. (2003). "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.". DNA Res. 10 (1): 49–57. PMID 12693554.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T (2005). "Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.". Cancer Cell 7 (1): 25–37. doi:10.1016/j.ccr.2004.11.021. PMID 15652747.
Chang P, Coughlin M, Mitchison TJ (2006). "Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function.". Nat. Cell Biol. 7 (11): 1133–9. doi:10.1038/ncb1322. PMID 16244666.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Gelmini S, Quattrone S, Malentacchi F, et al. (2007). "Tankyrase-1 mRNA expression in bladder cancer and paired urine sediment: preliminary experience.". Clin. Chem. Lab. Med. 45 (7): 862–6. doi:10.1515/CCLM.2007.133. PMID 17617028.