TNFAIP1

From Wikipedia, the free encyclopedia

Tumor necrosis factor, alpha-induced protein 1 (endothelial)

Identifiers

TNFAIP1; B61; B12; EDP1; MGC2317

External IDs

OMIM: 191161 MGI: 104961 HomoloGene: 22519

Gene ontology
Molecular Function:	• molecular_function • voltage-gated potassium channel activity • protein binding
Cellular Component:	• cellular_component • voltage-gated potassium channel complex • membrane
Biological Process:	• potassium ion transport • immune response • embryonic development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_021137 (mRNA)
NP_066960 (protein)

NM_009395 (mRNA)
NP_033421 (protein)

Location

Chr 17: 23.69 - 23.7 Mb

Chr 11: 78.34 - 78.35 Mb

Pubmed search

[1]

[2]

Tumor necrosis factor, alpha-induced protein 1 (endothelial), also known as TNFAIP1, is a human gene.^[1]

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.^[1]

[edit] References

^ ^a ^b Entrez Gene: TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial).

[edit] Further reading

Wolf FW, Marks RM, Sarma V, et al. (1992). "Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene.". J. Biol. Chem. 267 (2): 1317-26. PMID 1370465.
Holzman LB, Marks RM, Dixit VM (1990). "A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein.". Mol. Cell. Biol. 10 (11): 5830-8. PMID 2233719.
Dixit VM, Green S, Sarma V, et al. (1990). "Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin.". J. Biol. Chem. 265 (5): 2973-8. PMID 2406243.
Pandey A, Shao H, Marks RM, et al. (1995). "Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis.". Science 268 (5210): 567-9. PMID 7536959.
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs.". Genome Res. 11 (10): 1758-65. doi:10.1101/gr.180101. PMID 11591653.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Link CD, Taft A, Kapulkin V, et al. (2003). "Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model.". Neurobiol. Aging 24 (3): 397-413. PMID 12600716.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391-6. doi:10.1073/pnas.0507066103. PMID 16565220.