TMEM142A

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Transmembrane protein 142A
Identifiers
Symbol(s)	TMEM142A; CRACM1; FLJ14466; ORAI1
External IDs	OMIM: 610277 MGI: 1925542 HomoloGene: 13117
Gene ontology Molecular Function: • ion channel activity • calcium ion binding • store-operated calcium channel activity Cellular Component: • integral to plasma membrane • membrane Biological Process: • ion transport • calcium ion transport • immune response • positive regulation of calcium ion transport
Orthologs
	Human	Mouse
Entrez	84876	109305
Ensembl	ENSG00000182500	ENSMUSG00000049686
Uniprot	Q96D31	Q8BWG9
Refseq	NM_032790 (mRNA) NP_116179 (protein)	NM_175423 (mRNA) NP_780632 (protein)
Location	Chr 12: 120.55 - 120.56 Mb	Chr 5: 123.28 - 123.29 Mb
Pubmed search	[1]	[2]

Transmembrane protein 142A, also known as TMEM142A, is a human gene. Most common name orai. Three homologs, orai1-3. Plasma membrane spanning, possibly forming tetramers. Store operated regulation through STIM1-2.