THYN1

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Thymocyte nuclear protein 1
Identifiers
Symbol(s) THYN1; HSPC144; MDS012; MGC12187; MY105; THY28; THY28KD
External IDs MGI: 1925112 HomoloGene: 8575
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 29087 77862
Ensembl ENSG00000151500 ENSMUSG00000035443
Uniprot Q9P016 Q8BJZ7
Refseq NM_001037304 (mRNA)
NP_001032381 (protein)		 NM_144543 (mRNA)
NP_653126 (protein)
Location Chr 11: 133.62 - 133.63 Mb Chr 9: 26.75 - 26.76 Mb
Pubmed search [1] [2]

Thymocyte nuclear protein 1, also known as THYN1, is a human gene.[1]

This gene encodes a protein that is highly conserved among vertebrates and plant species and may be involved in the induction of apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described.[1]

[edit] References

  1. ^ a b Entrez Gene: THYN1 thymocyte nuclear protein 1.

[edit] Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548. 
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546-60. PMID 11042152. 
  • Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts.". Mol. Vis. 8: 196-204. PMID 12107411. 
  • Miyaji H, Yoshimoto T, Asakura H, et al. (2003). "Molecular cloning and characterization of the mouse thymocyte protein gene.". Gene 297 (1-2): 189-96. PMID 12384300. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Jiang X, Toyota H, Takada E, et al. (2004). "Modulation of mThy28 nuclear protein expression during thymocyte development.". Tissue & cell 35 (6): 471-8. PMID 14580360. 
  • Jiang XZ, Toyota H, Yoshimoto T, et al. (2004). "Anti-IgM-induced down-regulation of nuclear Thy28 protein expression in Ramos B lymphoma cells.". Apoptosis 8 (5): 509-19. PMID 14601557. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Song AX, Chang YG, Gao YG, et al. (2005). "Identification, expression, and purification of a unique stable domain from human HSPC144 protein.". Protein Expr. Purif. 42 (1): 146-52. doi:10.1016/j.pep.2005.03.008. PMID 15939300. 
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