Thiosulfate sulfurtransferase

From Wikipedia, the free encyclopedia

In enzymology, a thiosulfate sulfurtransferase (EC 2.8.1.1) is an enzyme that catalyzes the chemical reaction

thiosulfate + cyanide $\rightleftharpoons$ sulfite + thiocyanate

Thus, the two substrates of this enzyme are thiosulfate and cyanide, whereas its two products are sulfite and thiocyanate.

This enzyme belongs to the family of transferases, specifically the sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:cyanide sulfurtransferase. Other names in common use include thiosulfate cyanide transsulfurase, thiosulfate thiotransferase, rhodanese, and rhodanase.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes 1BOH, 1BOI, 1DP2, 1E0C, 1H4K, 1H4M, 1ORB, 1RHD, 1RHS, 1UAR, and 2ORA.

[edit] References

IUBMB entry for 2.8.1.1
BRENDA references for 2.8.1.1 (Recommended.)
PubMed references for 2.8.1.1
PubMed Central references for 2.8.1.1
Google Scholar references for 2.8.1.1
Sorbo BH (1953). "Crystalline rhodanese. I. Purification and physicochemical examination". Acta Chem. Scand. 7: 1129–1136.
Sorbo BH (1953). "Crystalline rhodanese. II. The enzyme catalyzed reaction". Acta Chem. Scand. 7: 1137–1145.
Westley J and Green JR (1959). "Crystalline beef kidney rhodanese". J. Biol. Chem. 234: 2325–2326.