Thiophene-2-carbonyl-CoA monooxygenase

From Wikipedia, the free encyclopedia

In enzymology, a thiophene-2-carbonyl-CoA monooxygenase (EC 1.14.99.35) is an enzyme that catalyzes the chemical reaction

thiophene-2-carbonyl-CoA + AH₂ + O₂ 5-hydroxythiophene-2-carbonyl-CoA + A + H₂O

The three substrates of this enzyme are thiophene-2-carbonyl-CoA, AH2, and O₂, whereas its 3 products are 5-hydroxythiophene-2-carbonyl-CoA, A, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase. Other names in common use include thiophene-2-carboxyl-CoA dehydrogenase, thiophene-2-carboxyl-CoA hydroxylase, and thiophene-2-carboxyl-CoA monooxygenase.

[edit] References

• IUBMB entry for 1.14.99.35
• BRENDA references for 1.14.99.35 (Recommended.)
• PubMed references for 1.14.99.35
• PubMed Central references for 1.14.99.35
• Google Scholar references for 1.14.99.35
• Bambauer A, Rainey FA, Stackebrandt E, Winter J (1998). "Characterization of Aquamicrobium defluvii gen. nov. sp. nov., a thiophene-2-carboxylate-metabolizing bacterium from activated sludge". Arch. Microbiol. 169: 293–302. doi:10.1007/s002030050575. PMID 9531630. 

[edit] External links

• IUBMB entry for 1.14.99.35

• KEGG entry for 1.14.99.35

• BRENDA entry for 1.14.99.35

• NiceZyme view of 1.14.99.35

• EC2PDB: PDB structures for 1.14.99.35

• PRIAM entry for 1.14.99.35

• PUMA2 entry for 1.14.99.35

• IntEnz: Integrated Enzyme entry for 1.14.99.35

• MetaCyc entry for 1.14.99.35

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050603: thiophene-2-carbonyl-CoA monooxygenase

• AMIGO entry for GO code 0050603: thiophene-2-carbonyl-CoA monooxygenase