Thioacetic acid

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Skeletal formula of thioacetic acid
Skeletal formula of thioacetic acid

Thioacetic acid is an organic compound with the molecular formula CH3COSH. It is the sulfur equivalent of acetic acid (AcSH) with a lower boiling point (88-91.5°C). It is used in organic chemistry for the introduction of thiol groups in molecules.

In one application the reagent is used with AIBN in a free radical mediated nucleophilic addition to an exocyclic alkene forming a thioester [1] :

thioacetic acid application

[edit] References

  1. ^ Synthesis of methyl 6-deoxy-4-O-(sodium sulfonato)-α-Ltalopyranoside, its C-4 epimer and both isosteric [4-C-(potassium sulfonatomethyl)] derivativesLászló Lázár, Magdolna Csávás, Anikó Borbás, Gyöngyi Gyémánt, and András Lipták ARKIVOC 2004 (vii) 196-207 Link