TFDP2

From Wikipedia, the free encyclopedia

Transcription factor Dp-2 (E2F dimerization partner 2)

PDB rendering based on 1cf7.

Available structures: 1cf7

Identifiers

Symbol(s)

TFDP2; DP2; Dp-2

External IDs

OMIM: 602160 MGI: 107167 HomoloGene: 4578

Gene ontology
Molecular Function:	• transcription factor activity • transcription cofactor activity
Cellular Component:	• nucleus • transcription factor complex
Biological Process:	• regulation of progression through cell cycle • DNA metabolic process • transcription • regulation of transcription, DNA-dependent • regulation of transcription from RNA polymerase II promoter • cell cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006286 (mRNA)
NP_006277 (protein)

XM_975033 (mRNA)
XP_980127 (protein)

Location

Chr 3: 143.15 - 143.35 Mb

Chr 9: 96.01 - 96.13 Mb

Pubmed search

[1]

[2]

Transcription factor Dp-2 (E2F dimerization partner 2), also known as TFDP2, is a human gene.^[1]

[edit] References

^ Entrez Gene: TFDP2 transcription factor Dp-2 (E2F dimerization partner 2).

[edit] Further reading

Wu CL, Zukerberg LR, Ngwu C, et al. (1995). "In vivo association of E2F and DP family proteins.". Mol. Cell. Biol. 15 (5): 2536-46. PMID 7739537.
Zhang Y, Chellappan SP (1995). "Cloning and characterization of human DP2, a novel dimerization partner of E2F.". Oncogene 10 (11): 2085-93. PMID 7784053.
Rogers KT, Higgins PD, Milla MM, et al. (1996). "DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo.". Proc. Natl. Acad. Sci. U.S.A. 93 (15): 7594-9. PMID 8755520.
Zhang Y, Venkatraj VS, Fischer SG, et al. (1997). "Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family.". Genomics 39 (1): 95-8. doi:10.1006/geno.1996.4473. PMID 9027491.
Loiseau L, Pasteau S, Brun G (1998). "Molecular cloning and expression pattern of the DP members of the chicken E2F transcription factor.". Gene Expr. 6 (5): 259-73. PMID 9368098.
Trimarchi JM, Fairchild B, Verona R, et al. (1998). "E2F-6, a member of the E2F family that can behave as a transcriptional repressor.". Proc. Natl. Acad. Sci. U.S.A. 95 (6): 2850-5. PMID 9501179.
Gaubatz S, Wood JG, Livingston DM (1998). "Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6.". Proc. Natl. Acad. Sci. U.S.A. 95 (16): 9190-5. PMID 9689056.
Zheng N, Fraenkel E, Pabo CO, Pavletich NP (1999). "Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP.". Genes Dev. 13 (6): 666-74. PMID 10090723.
Korz C, Pscherer A, Benner A, et al. (2002). "Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes.". Blood 99 (12): 4554-61. PMID 12036888.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Park KK, Deok Ahn J, Lee IK, et al. (2003). "Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP.". Biochem. Biophys. Res. Commun. 308 (4): 689-97. PMID 12927774.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.