TFAP4

From Wikipedia, the free encyclopedia

Transcription factor AP-4 (activating enhancer binding protein 4)

Identifiers

External IDs

OMIM: 600743 MGI: 103239 HomoloGene: 2424

Gene ontology
Molecular Function:	• RNA polymerase II transcription factor activity, enhancer binding • transcription coactivator activity • transcription regulator activity
Cellular Component:	• nucleus
Biological Process:	• regulation of transcription from RNA polymerase II promoter • multicellular organismal development • regulation of transcription

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_003223 (mRNA)
NP_003214 (protein)

XM_978076 (mRNA)
XP_983170 (protein)

Location

Chr 16: 4.25 - 4.26 Mb

Chr 16: 4.46 - 4.47 Mb

Pubmed search

[1]

[2]

Transcription factor AP-4 (activating enhancer binding protein 4), also known as TFAP4, is a human gene.^[1]

[edit] References

^ Entrez Gene: TFAP4 transcription factor AP-4 (activating enhancer binding protein 4).

[edit] Further reading

Hu YF, Lüscher B, Admon A, et al. (1991). "Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.". Genes Dev. 4 (10): 1741–52. PMID 2123466.
Mermod N, Williams TJ, Tjian R (1988). "Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro.". Nature 332 (6164): 557–61. doi:10.1038/332557a0. PMID 2833704.
Ou SH, Garcia-Martínez LF, Paulssen EJ, Gaynor RB (1994). "Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.". J. Virol. 68 (11): 7188–99. PMID 7933101.
Lewis TB, Wood S, Michaelis EK, et al. (1996). "Localization of a gene for a glutamate binding subunit of a NMDA receptor (GRINA) to 8q24.". Genomics 32 (1): 131–3. doi:10.1006/geno.1996.0088. PMID 8786101.
Petersenn S, Rasch AC, Heyens M, Schulte HM (1998). "Structure and regulation of the human growth hormone-releasing hormone receptor gene.". Mol. Endocrinol. 12 (2): 233–47. PMID 9482665.
King-Jones K, Korge G, Lehmann M (1999). "The helix-loop-helix proteins dAP-4 and daughterless bind both in vitro and in vivo to SEBP3 sites required for transcriptional activation of the Drosophila gene Sgs-4.". J. Mol. Biol. 291 (1): 71–82. doi:10.1006/jmbi.1999.2963. PMID 10438607.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16.". Nature 432 (7020): 988–94. doi:10.1038/nature03187. PMID 15616553.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.