Taurine-pyruvate aminotransferase

From Wikipedia, the free encyclopedia

In enzymology, a taurine-pyruvate aminotransferase (EC 2.6.1.77) is an enzyme that catalyzes the chemical reaction

taurine + pyruvate L-alanine + 2-sulfoacetaldehyde

Thus, the two substrates of this enzyme are taurine and pyruvate, whereas its two products are L-alanine and 2-sulfoacetaldehyde.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is taurine:pyruvate aminotransferase. This enzyme is also called Tpa. This enzyme participates in taurine and hypotaurine metabolism.

[edit] References

• IUBMB entry for 2.6.1.77
• BRENDA references for 2.6.1.77 (Recommended.)
• PubMed references for 2.6.1.77
• PubMed Central references for 2.6.1.77
• Google Scholar references for 2.6.1.77
• Laue H, Cook AM (2000). "Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia". Eur. J. Biochem. 267: 6841–8. doi:10.1046/j.1432-1033.2000.01782.x. PMID 11082195. 
• Cook AM, Denger K (2002). "Dissimilation of the C2 sulfonates". Arch. Microbiol. 179: 1–6. doi:10.1007/s00203-002-0497-0. PMID 12471498. 
• Masepohl B, Fuhrer F, Klipp W (2001). "Genetic analysis of a Rhodobacter capsulatus gene region involved in utilization of taurine as a sulfur source". FEMS. Microbiol. Lett. 205: 105–11. doi:10.1111/j.1574-6968.2001.tb10932.x. PMID 11728723. 

[edit] External links

• IUBMB entry for 2.6.1.77

• KEGG entry for 2.6.1.77

• BRENDA entry for 2.6.1.77

• NiceZyme view of 2.6.1.77

• EC2PDB: PDB structures for 2.6.1.77

• PRIAM entry for 2.6.1.77

• PUMA2 entry for 2.6.1.77

• IntEnz: Integrated Enzyme entry for 2.6.1.77

• MetaCyc entry for 2.6.1.77

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0031299: taurine-pyruvate aminotransferase

• AMIGO entry for GO code 0031299: taurine-pyruvate aminotransferase