Tagatose-6-phosphate kinase

From Wikipedia, the free encyclopedia

In enzymology, a tagatose-6-phosphate kinase (EC 2.7.1.144) is an enzyme that catalyzes the chemical reaction

ATP + D-tagatose 6-phosphate ADP + D-tagatose 1,6-bisphosphate

Thus, the two substrates of this enzyme are ATP and D-tagatose 6-phosphate, whereas its two products are ADP and D-tagatose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-tagatose-6-phosphate 1-phosphotransferase. This enzyme participates in galactose metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 2AWD, 2F02, 2JG1, 2JGV, and 2Q5R.

[edit] References

• IUBMB entry for 2.7.1.144
• BRENDA references for 2.7.1.144 (Recommended.)
• PubMed references for 2.7.1.144
• PubMed Central references for 2.7.1.144
• Google Scholar references for 2.7.1.144
• Nobelmann B, Lengeler JW (1995). "Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli". Biochim. Biophys. Acta. 1262: 69–72. PMID 7772602. 

[edit] External links

The CAS registry number for this enzyme class is 39434-00-9.

• IUBMB entry for 2.7.1.144

• KEGG entry for 2.7.1.144

• BRENDA entry for 2.7.1.144

• NiceZyme view of 2.7.1.144

• EC2PDB: PDB structures for 2.7.1.144

• PRIAM entry for 2.7.1.144

• PUMA2 entry for 2.7.1.144

• IntEnz: Integrated Enzyme entry for 2.7.1.144

• MetaCyc entry for 2.7.1.144

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0009024: tagatose-6-phosphate kinase

• AMIGO entry for GO code 0009024: tagatose-6-phosphate kinase