Tabersonine 16-O-methyltransferase

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In enzymology, a tabersonine 16-O-methyltransferase (EC 2.1.1.94) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 16-hydroxytabersonine $\rightleftharpoons$ S-adenosyl-L-homocysteine + 16-methoxytabersonine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 16-hydroxytabersonine, whereas its two products are S-adenosylhomocysteine and 16-methoxytabersonine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase. Other names in common use include 11-demethyl-17-deacetylvindoline 11-methyltransferase, 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase, S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline, and 11-O-methyltransferase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

[edit] References

IUBMB entry for 2.1.1.94
BRENDA references for 2.1.1.94 (Recommended.)
PubMed references for 2.1.1.94
PubMed Central references for 2.1.1.94
Google Scholar references for 2.1.1.94
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Fahn W, Laussermair E, Deus-Neumann B and Stockigt J (1985). "Late enzymes of vindoline biosynthesis S-Adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methylase and unspecific acetylesterase". Plant Cell Rep. 4: 337–340.