T2-induced deoxynucleotide kinase

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In enzymology, a T2-induced deoxynucleotide kinase (EC 2.7.4.12) is an enzyme that catalyzes the chemical reaction

ATP + dGMP (or dTMP) ADP + dGDP (or dTDP)

The 3 substrates of this enzyme are ATP, dGMP, and dTMP, whereas its 3 products are ADP, dGDP, and dTDP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)NMP phosphotransferase.

[edit] References

• IUBMB entry for 2.7.4.12
• BRENDA references for 2.7.4.12 (Recommended.)
• PubMed references for 2.7.4.12
• PubMed Central references for 2.7.4.12
• Google Scholar references for 2.7.4.12
• BELLO LJ, BESSMAN MJ (1963). "The enzymology of virus-infected bacteria. IV. Purification and properties of the deoxynucleotide kinase induced by bacteriophage T2". J. Biol. Chem. 238: 1777–87. PMID 13967158. 

[edit] External links

The CAS registry number for this enzyme class is 37278-99-2.

• IUBMB entry for 2.7.4.12

• KEGG entry for 2.7.4.12

• BRENDA entry for 2.7.4.12

• NiceZyme view of 2.7.4.12

• EC2PDB: PDB structures for 2.7.4.12

• PRIAM entry for 2.7.4.12

• PUMA2 entry for 2.7.4.12

• IntEnz: Integrated Enzyme entry for 2.7.4.12

• MetaCyc entry for 2.7.4.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050316: T2-induced deoxynucleotide kinase

• AMIGO entry for GO code 0050316: T2-induced deoxynucleotide kinase