Synaptojanin

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synaptojanin 1
Identifiers
Symbol	SYNJ1
Entrez	8867
HUGO	11503
OMIM	604297
RefSeq	NM_003895
UniProt	O43426
Other data
Locus	Chr. 21 q22.2

synaptojanin 2
Identifiers
Symbol	SYNJ2
Entrez	8871
HUGO	11504
OMIM	609410
RefSeq	NM_003898
UniProt	O15056
Other data
Locus	Chr. 6 q25.3

Synaptojanin is a protein involved in vesicle uncoating in neurons. This is an important regulatory lipid phosphatase. It dephosphorylates the D-5 position phosphate from Phosphatidylinositol (3,4,5)-trisphosphate and Phosphatidylinositol (4,5)-bisphosphate. It belongs to family of 5-phosphatases, which are structurally unrelated to D-3 inositol phosphatases like PTEN.

[edit] External links

• MeSH Synaptojanin