SV2B

From Wikipedia, the free encyclopedia

Synaptic vesicle glycoprotein 2B

Identifiers

SV2B; HsT19680; KIAA0735

External IDs

OMIM: 185861 MGI: 1927338 HomoloGene: 32236

Gene ontology
Molecular Function:	• transporter activity
Cellular Component:	• synaptic vesicle • membrane • integral to membrane • synapse
Biological Process:	• neurotransmitter transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014848 (mRNA)
NP_055663 (protein)

NM_153579 (mRNA)
NP_705807 (protein)

Location

Chr 15: 89.57 - 89.64 Mb

Chr 7: 74.99 - 75.18 Mb

Pubmed search

[1]

[2]

Synaptic vesicle glycoprotein 2B, also known as SV2B, is a human gene.^[1]

[edit] References

^ Entrez Gene: SV2B synaptic vesicle glycoprotein 2B.

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Lazzell DR, Belizaire R, Thakur P, et al. (2005). "SV2B regulates synaptotagmin 1 by direct interaction.". J. Biol. Chem. 279 (50): 52124-31. doi:10.1074/jbc.M407502200. PMID 15466855.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Janz R, Goda Y, Geppert M, et al. (2000). "SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.". Neuron 24 (4): 1003-16. PMID 10624962.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (5): 277-86. PMID 9872452.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353-8. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107-13. doi:10.1006/abio.1996.0138. PMID 8619474.
Bajjalieh SM, Peterson K, Linial M, Scheller RH (1993). "Brain contains two forms of synaptic vesicle protein 2.". Proc. Natl. Acad. Sci. U.S.A. 90 (6): 2150-4. PMID 7681585.