Sulfapyridine
From Wikipedia, the free encyclopedia
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Sulfapyridine
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| Systematic (IUPAC) name | |
| 4-amino-N-pyridin-2-ylbenzenesulfonamide | |
| Identifiers | |
| CAS number | |
| ATC code | J01 |
| PubChem | |
| Chemical data | |
| Formula | C11H11N3O2S |
| Mol. mass | 249.29 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
| Original laboratory code: M&B 693. Sulfapyridine is a sulfonamide antibacterial. Along with mesalamine, it forms the drug sulfasalazine.
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Discovered by May & Baker Ltd and logged in their Test Book on 2 November 1937 under Code No M&B693. Successfully used to treat Winston Churchill's bacterial pneumonia in 1942. In a subsequent radio broadcast he said "This admirable M&B from which I did not suffer any inconvenience, was used at the earliest moment and, after a week's fever, the intruders were repulsed." In 1944 M&B693 also saved Nero, the Royal Circus lion, from pneumonia.[Glasgow Evening News January 1944.]

