Succinylglutamate desuccinylase

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In enzymology, a succinylglutamate desuccinylase (EC 3.5.1.96) is an enzyme that catalyzes the chemical reaction

N-succinyl-L-glutamate + H₂O $\rightleftharpoons$ succinate + L-glutamate

Thus, the two substrates of this enzyme are N-succinyl-L-glutamate and H₂O, whereas its two products are succinate and L-glutamate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-succinyl-L-glutamate amidohydrolase. Other names in common use include N2-succinylglutamate desuccinylase, SGDS, and AstE. This enzyme participates in arginine and proline metabolism.

[edit] References

IUBMB entry for 3.5.1.96
BRENDA references for 3.5.1.96 (Recommended.)
PubMed references for 3.5.1.96
PubMed Central references for 3.5.1.96
Google Scholar references for 3.5.1.96
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Cunin R, Glansdorff N, Pierard A and Stalon V (1987). "Erratum report: Biosynthesis and metabolism of arginine in bacteria". Microbiol. Rev. 51: 178.
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Schneider BL, Kiupakis AK, Reitzer LJ (1998). "Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli". J. Bacteriol. 180: 4278–86. PMID 9696779.