Succinate-hydroxymethylglutarate CoA-transferase

From Wikipedia, the free encyclopedia

In enzymology, a succinate-hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + 3-hydroxy-3-methylglutarate succinate + (S)-3-hydroxy-3-methylglutaryl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and 3-hydroxy-3-methylglutarate, whereas its two products are succinate and (S)-3-hydroxy-3-methylglutaryl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:3-hydroxy-3-methylglutarate CoA-transferase. Other names in common use include hydroxymethylglutarate coenzyme A-transferase, and dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase.

[edit] References

• IUBMB entry for 2.8.3.13
• BRENDA references for 2.8.3.13 (Recommended.)
• PubMed references for 2.8.3.13
• PubMed Central references for 2.8.3.13
• Google Scholar references for 2.8.3.13
• Deana R, Rigoni F, Deana AD, Galzigna L (1981). "Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver". Biochim. Biophys. Acta. 662: 119–24. PMID 6946836. 

[edit] External links

The CAS registry number for this enzyme class is 80237-90-7.

• IUBMB entry for 2.8.3.13

• KEGG entry for 2.8.3.13

• BRENDA entry for 2.8.3.13

• NiceZyme view of 2.8.3.13

• EC2PDB: PDB structures for 2.8.3.13

• PRIAM entry for 2.8.3.13

• PUMA2 entry for 2.8.3.13

• IntEnz: Integrated Enzyme entry for 2.8.3.13

• MetaCyc entry for 2.8.3.13

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047369: succinate-hydroxymethylglutarate CoA-transferase

• AMIGO entry for GO code 0047369: succinate-hydroxymethylglutarate CoA-transferase