STX16

From Wikipedia, the free encyclopedia

Syntaxin 16

Identifiers

STX16; MGC90328; SYN16; hsyn16

External IDs

OMIM: 603666 MGI: 1923396 HomoloGene: 2791

Gene ontology
Molecular Function:	• SNAP receptor activity • protein transporter activity
Cellular Component:	• cytoplasm • microsome • Golgi apparatus • Golgi stack • membrane • integral to membrane
Biological Process:	• intracellular protein transport • intra-Golgi vesicle-mediated transport

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_001001433 (mRNA)
NP_001001433 (protein)

NM_172675 (mRNA)
NP_766263 (protein)

Location

n/a

Chr 2: 173.72 - 173.74 Mb

Pubmed search

[1]

[2]

Syntaxin 16, also known as STX16, is a human gene.^[1]

[edit] References

^ Entrez Gene: STX16 syntaxin 16.

[edit] Further reading

Tang BL, Low DY, Lee SS, et al. (1998). "Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins.". Biochem. Biophys. Res. Commun. 242 (3): 673–9. doi:10.1006/bbrc.1997.8029. PMID 9464276.
Simonsen A, Bremnes B, Rønning E, et al. (1998). "Syntaxin-16, a putative Golgi t-SNARE.". Eur. J. Cell Biol. 75 (3): 223–31. PMID 9587053.
Yu Y, Zhang C, Zhou G, et al. (2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.". Genome Res. 11 (8): 1392–403. doi:10.1101/gr.175501. PMID 11483580.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
Mallard F, Tang BL, Galli T, et al. (2002). "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform.". J. Cell Biol. 156 (4): 653–64. doi:10.1083/jcb.200110081. PMID 11839770.
Dulubova I, Yamaguchi T, Gao Y, et al. (2002). "How Tlg2p/syntaxin 16 'snares' Vps45.". EMBO J. 21 (14): 3620–31. doi:10.1093/emboj/cdf381. PMID 12110575.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark AG, Glanowski S, Nielsen R, et al. (2003). "Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios.". Science 302 (5652): 1960–3. doi:10.1126/science.1088821. PMID 14671302.
Tai G, Lu L, Wang TL, et al. (2005). "Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network.". Mol. Biol. Cell 15 (9): 4011–22. doi:10.1091/mbc.E03-12-0876. PMID 15215310.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Linglart A, Gensure RC, Olney RC, et al. (2005). "A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS.". Am. J. Hum. Genet. 76 (5): 804–14. doi:10.1086/429932. PMID 15800843.
Amessou M, Fradagrada A, Falguières T, et al. (2007). "Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins.". J. Cell. Sci. 120 (Pt 8): 1457–68. doi:10.1242/jcs.03436. PMID 17389686.