STARD13

From Wikipedia, the free encyclopedia

START domain containing 13

PDB rendering based on 2h80.

Available structures: 2h80, 2pso

Identifiers

Symbol(s)

STARD13; DLC2; FLJ37385; GT650

External IDs

OMIM: 609866 MGI: 2385331 HomoloGene: 64844

Gene ontology
Molecular Function:	• GTPase activator activity
Cellular Component:	• intracellular
Biological Process:	• cell cycle • signal transduction • negative regulation of progression through cell cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_178008 (mRNA)
NP_821076 (protein)

NM_146258 (mRNA)
NP_666370 (protein)

Location

Chr 13: 32.58 - 32.76 Mb

n/a

Pubmed search

[1]

[2]

START domain containing 13, also known as STARD13, is a human gene.^[1]

[edit] References

^ Entrez Gene: STARD13 START domain containing 13.

[edit] Further reading

Couch FJ, Rommens JM, Neuhausen SL, et al. (1997). "Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.". Genomics 36 (1): 86-99. PMID 8812419.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ching YP, Wong CM, Chan SF, et al. (2003). "Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma.". J. Biol. Chem. 278 (12): 10824-30. doi:10.1074/jbc.M208310200. PMID 12531887.
Day CL, Puthalakath H, Skea G, et al. (2004). "Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands.". Biochem. J. 377 (Pt 3): 597-605. doi:10.1042/BJ20031251. PMID 14561217.
Nagaraja GM, Kandpal RP (2004). "Chromosome 13q12 encoded Rho GTPase activating protein suppresses growth of breast carcinoma cells, and yeast two-hybrid screen shows its interaction with several proteins.". Biochem. Biophys. Res. Commun. 313 (3): 654-65. PMID 14697242.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522-8. doi:10.1038/nature02379. PMID 15057823.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Leung TH, Ching YP, Yam JW, et al. (2005). "Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity.". Proc. Natl. Acad. Sci. U.S.A. 102 (42): 15207-12. doi:10.1073/pnas.0504501102. PMID 16217026.