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| SraE/RygA/RygB family RNA |
 |
| Type: |
Gene; sRNA; |
| 2° structure: |
Predicted; PFOLD |
| Seed alignment: |
Bateman A |
| Avg length: |
86.9 nucleotides |
| Avg identity: |
82% |
|
The SraA RNA is a small non-coding RNA that was discovered in E. coli during two large scale screens.[1][2] SraE (also known as RygB) is highly abundant in stationary phase, but low levels could be detected in exponentially growing cells as well. RygB is adjacent to RygA a closely related RNA. The function of these RNAs is unknown but it seems likely given that they bind to the Hfq protein that they regulate gene expression by antisense binding.
[edit] References
- ^ Argaman, L; Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli". Curr Biol 11: 941–950. doi:10.1016/S0960-9822(01)00270-6. PMID 11448770.
- ^ Wassarman, KM; Repoila F, Rosenow C, Storz G, Gottesman S (2001). "Identification of novel small RNAs using comparative genomics and microarrays". Genes Dev 15: 1637–1651. doi:10.1101/gad.901001. PMID 11445539.
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