SPRR1A

From Wikipedia, the free encyclopedia

Small proline-rich protein 1A

Identifiers

External IDs

OMIM: 182265 MGI: 106660 HomoloGene: 68495

Gene ontology
Molecular Function:	• structural molecule activity • protein binding, bridging
Cellular Component:	• cornified envelope
Biological Process:	• epidermis development • peptide cross-linking • keratinocyte differentiation • keratinization

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005987 (mRNA)
NP_005978 (protein)

NM_009264 (mRNA)
NP_033290 (protein)

Location

Chr 1: 151.22 - 151.22 Mb

Chr 3: 92.57 - 92.57 Mb

Pubmed search

[1]

[2]

Small proline-rich protein 1A, also known as SPRR1A, is a human gene.^[1]

[edit] References

^ Entrez Gene: SPRR1A small proline-rich protein 1A.

[edit] Further reading

Greco MA, Lorand L, Lane WS, et al. (1995). "The pancornulins: a group of small proline rich-related cornified envelope precursors with bifunctional capabilities in isopeptide bond formation.". J. Invest. Dermatol. 104 (2): 204-10. PMID 7829876.
Robinson PA, Marley JJ, High AS, Hume WJ (1994). "Differential expression of protease inhibitor and small proline-rich protein genes between normal human oral tissue and odontogenic keratocysts.". Arch. Oral Biol. 39 (3): 251-9. PMID 8018055.
Gibbs S, Fijneman R, Wiegant J, et al. (1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins.". Genomics 16 (3): 630-7. doi:10.1006/geno.1993.1240. PMID 8325635.
Fujimoto W, Nakanishi G, Arata J, Jetten AM (1997). "Differential expression of human cornifin alpha and beta in squamous differentiating epithelial tissues and several skin lesions.". J. Invest. Dermatol. 108 (2): 200-4. PMID 9008234.
Robinson NA, Lapic S, Welter JF, Eckert RL (1997). "S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes.". J. Biol. Chem. 272 (18): 12035-46. PMID 9115270.
Reddy SP, Konkin T, Wu R (1999). "Structure and organization of the genes encoding mouse small proline-rich proteins, mSPRR1A and 1B.". Gene 224 (1-2): 59-66. PMID 9931436.
Candi E, Tarcsa E, Idler WW, et al. (1999). "Transglutaminase cross-linking properties of the small proline-rich 1 family of cornified cell envelope proteins. Integration with loricrin.". J. Biol. Chem. 274 (11): 7226-37. PMID 10066784.
Lee CH, Marekov LN, Kim S, et al. (2000). "Small proline-rich protein 1 is the major component of the cell envelope of normal human oral keratinocytes.". FEBS Lett. 477 (3): 268-72. PMID 10908733.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788-95. PMID 11076863.
Cabral A, Voskamp P, Cleton-Jansen AM, et al. (2001). "Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function.". J. Biol. Chem. 276 (22): 19231-7. doi:10.1074/jbc.M100336200. PMID 11279051.
Bonilla IE, Tanabe K, Strittmatter SM (2002). "Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth.". J. Neurosci. 22 (4): 1303-15. PMID 11850458.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.