South Dakota Highway 38
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| Highway 38 |
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| Length: | 65.3 mi (105.1 km) | ||||||||
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| West end: |  SD 37 in Mitchell |
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| Major junctions: |
 US 81 in Salem  I-90 / SD 19 in Humboldt I-90 in Buffalo Ridge |
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| East end: |  I-29 in Sioux Falls |
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South Dakota Highway 38 is a state highway in the state of South Dakota. The highway runs from Mitchell to Sioux Falls.
