SNRK

From Wikipedia, the free encyclopedia

SNF related kinase

Identifiers

SNRK; DKFZp779A1866; FLJ20224; HSNFRK; KIAA0096

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • magnesium ion binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• nucleus
Biological Process:	• protein amino acid phosphorylation • myeloid cell differentiation • regulation of neuron apoptosis

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_017719 (mRNA)
NP_060189 (protein)

NM_133741 (mRNA)
NP_598502 (protein)

Location

Chr 3: 43.3 - 43.37 Mb

n/a

Pubmed search

[1]

[2]

SNF related kinase, also known as SNRK, is a human gene.^[1]

[edit] References

^ Entrez Gene: SNRK SNF related kinase.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. PMID 12168954.
Nagase T, Miyajima N, Tanaka A, et al. (1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 2 (1): 37–43. PMID 7788527.
Becker W, Heukelbach J, Kentrup H, Joost HG (1996). "Molecular cloning and characterization of a novel mammalian protein kinase harboring a homology domain that defines a subfamily of serine/threonine kinases.". Eur. J. Biochem. 235 (3): 736–43. PMID 8654423.
Iacobelli M, Wachsman W, McGuire KL (2000). "Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein.". J. Immunol. 165 (2): 860–8. PMID 10878360.
Yoshida K, Yamada M, Nishio C, et al. (2000). "SNRK, a member of the SNF1 family, is related to low K(+)-induced apoptosis of cultured rat cerebellar granule neurons.". Brain Res. 873 (2): 274–82. PMID 10930554.
Bower KE, Zeller RW, Wachsman W, et al. (2002). "Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions.". J. Biol. Chem. 277 (38): 34967–77. doi:10.1074/jbc.M205048200. PMID 12087103.
Kertesz N, Samson J, Debacker C, et al. (2003). "Cloning and characterization of human and mouse SNRK sucrose non-fermenting protein (SNF-1)-related kinases.". Gene 294 (1-2): 13–24. PMID 12234663.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Jaleel M, McBride A, Lizcano JM, et al. (2005). "Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.". FEBS Lett. 579 (6): 1417–23. doi:10.1016/j.febslet.2005.01.042. PMID 15733851.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.