SNAPC4

From Wikipedia, the free encyclopedia

Small nuclear RNA activating complex, polypeptide 4, 190kDa

Identifiers

SNAPC4; FLJ13451; PTFalpha; SNAP190

External IDs

OMIM: 602777 MGI: 2443935 HomoloGene: 2321

Gene ontology
Molecular Function:	• transcription factor activity
Cellular Component:	• nucleus • snRNA-activating protein complex
Biological Process:	• regulation of transcription, DNA-dependent • snRNA transcription from RNA polymerase II promoter • snRNA transcription from RNA polymerase III promoter

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003086 (mRNA)
NP_003077 (protein)

NM_172339 (mRNA)
NP_758842 (protein)

Location

Chr 9: 138.39 - 138.41 Mb

Chr 2: 26.18 - 26.2 Mb

Pubmed search

[1]

[2]

Small nuclear RNA activating complex, polypeptide 4, 190kDa, also known as SNAPC4, is a human gene.^[1]

[edit] References

^ Entrez Gene: SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa.

[edit] Further reading

Henry RW, Sadowski CL, Kobayashi R, Hernandez N (1995). "A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III.". Nature 374 (6523): 653–6. doi:10.1038/374653a0. PMID 7715707.
Wong MW, Henry RW, Ma B, et al. (1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1.". Mol. Cell. Biol. 18 (1): 368–77. PMID 9418884.
Ma B, Hernandez N (2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.". J. Biol. Chem. 276 (7): 5027–35. doi:10.1074/jbc.M009301200. PMID 11056176.
Hovde S, Brooks A, Strong K, Geiger JH (2002). "Crystallization of the Oct-1/SNAP190 peptide/DNA complex.". Acta Crystallogr. D Biol. Crystallogr. 58 (Pt 3): 511–2. PMID 11856838.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Hinkley CS, Hirsch HA, Gu L, et al. (2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.". J. Biol. Chem. 278 (20): 18649–57. doi:10.1074/jbc.M204247200. PMID 12621023.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMID 15164053.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gu L, Esselman WJ, Henry RW (2005). "Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC.". J. Biol. Chem. 280 (30): 27697–704. doi:10.1074/jbc.M503206200. PMID 15955816.
Gu L, Husain-Ponnampalam R, Hoffmann-Benning S, Henry RW (2007). "The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III.". J. Biol. Chem. 282 (38): 27887–96. doi:10.1074/jbc.M702269200. PMID 17670747.