SNAG1

From Wikipedia, the free encyclopedia


Sorting nexin associated golgi protein 1
Identifiers
Symbol(s) SNAG1; MGC150827; MGC150829; SH3PX2; SH3PXD3B; SNX18
External IDs MGI: 2137642 HomoloGene: 14164
Orthologs
Human Mouse
Entrez 112574 170625
Ensembl ENSG00000178996 ENSMUSG00000042364
Uniprot Q96RF0 Q91ZR2
Refseq NM_052870 (mRNA)
NP_443102 (protein)		 NM_130796 (mRNA)
NP_570614 (protein)
Location Chr 5: 53.85 - 53.88 Mb Chr 13: 114.71 - 114.74 Mb
Pubmed search [1] [2]

Sorting nexin associated golgi protein 1, also known as SNAG1, is a human gene.[1]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.[1]

[edit] References

  1. ^ a b Entrez Gene: SNAG1 sorting nexin associated golgi protein 1.

[edit] Further reading

  • Seet LF, Hong W (2006). "The Phox (PX) domain proteins and membrane traffic.". Biochim. Biophys. Acta 1761 (8): 878-96. doi:10.1016/j.bbalip.2006.04.011. PMID 16782399. 
  • Worby CA, Dixon JE (2003). "Sorting out the cellular functions of sorting nexins.". Nat. Rev. Mol. Cell Biol. 3 (12): 919-31. doi:10.1038/nrm974. PMID 12461558. 
  • Xu Y, Seet LF, Hanson B, Hong W (2002). "The Phox homology (PX) domain, a new player in phosphoinositide signalling.". Biochem. J. 360 (Pt 3): 513-30. PMID 11736640. 
  • Thornhill PB, Cohn JB, Drury G, et al. (2008). "A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells.". FEBS Lett. 581 (23): 4455-62. doi:10.1016/j.febslet.2007.08.025. PMID 17761170. 
  • Ozyildirim AM, Wistow GJ, Gao J, et al. (2005). "The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts.". Invest. Ophthalmol. Vis. Sci. 46 (5): 1572-80. doi:10.1167/iovs.04-1380. PMID 15851553. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Schulze WX, Mann M (2004). "A novel proteomic screen for peptide-protein interactions.". J. Biol. Chem. 279 (11): 10756-64. doi:10.1074/jbc.M309909200. PMID 14679214. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Teasdale RD, Loci D, Houghton F, et al. (2001). "A large family of endosome-localized proteins related to sorting nexin 1.". Biochem. J. 358 (Pt 1): 7-16. PMID 11485546. 
 This article on a gene on chromosome 5 is a stub. You can help Wikipedia by expanding it.