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| Small nucleolar RNA SNORA48 |
 |
| Type: |
Gene; snRNA; guide; HACA-box; |
| 2° structure: |
Predicted; RNAalifold |
| Seed alignment: |
Marantidis E |
| Avg length: |
130.9 nucleotides |
| Avg identity: |
79% |
|
Small nucleolar RNA SNORA48 is a pseudouridylation guide H/ACA box snoRNA. This snoRNA was cloned by Kiss et al. (2004)[1] from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U3797 of 28S rRNA. The pseudouridylation of this residue was previously reported by Ofengand and Bakin (1997)[2]. The H/ACA box snoRNAs ACA48 and U67, and the C/D box snoRNA mgU6-77 share the same host gene (EIF4A1).
[edit] References
- ^ Kiss, AM; Jady BE, Bertrand E, Kiss T (2004). "Human box H/ACA pseudouridylation guide RNA machinery". Mol Cell Biol. 24: 5797–5807. doi:10.1128/MCB.24.13.5797-5807.2004. PMID 15199136.
- ^ Ofengand, J; Bakin A (1997). "Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts". J Mol Biol. 266: 246–268. doi:10.1006/jmbi.1996.0737. PMID 9047361.
[edit] External links
