Small nucleolar RNA R64/Z200 family

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Small nucleolar RNA R64/Z200 family

Type:	Gene; snRNA; guide; CD-box;
2° structure:	Predicted; PFOLD; Daub J
Seed alignment:	INFERNAL
Avg length:	94.2 nucleotides
Avg identity:	70%

This family of plant small nucleolar RNAs belong to the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. This family includes Arabidopsis thaliana snoRNA R64 and Oryza sativa snoRNAs Z200 and J16. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs [1].

[edit] References

[1] Galardi, S; Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I (2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Mol Cell Biol 22: 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMID 12215523.
[2] Marker, C; Zemann A, Terhorst T, Kiefmann M, Kastenmayer JP, Green P, Bachellerie JP, Brosius J, Huttenhofer A (2002). "Experimental RNomics: identification of 140 candidates for small non-messenger RNAs in the plant Arabidopsis thaliana". Curr Biol 12: 2002–2013. doi:10.1016/S0960-9822(02)01304-0. PMID 12477388.