Small nuclear ribonucleoprotein polypeptide E

From Wikipedia, the free encyclopedia

Identifiers

SNRPE; B-raf; SME

External IDs

OMIM: 128260 MGI: 98346 HomoloGene: 37729

Gene ontology
Molecular Function:	• RNA binding • protein binding
Cellular Component:	• nucleus • spliceosome • small nuclear ribonucleoprotein complex
Biological Process:	• spliceosome assembly • mRNA processing • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_003094 (mRNA)
NP_003085 (protein)

NM_009227 (mRNA)
NP_033253 (protein)

Location

Chr 1: 202.1 - 202.11 Mb

n/a

Pubmed search

[1]

[2]

Small nuclear ribonucleoprotein polypeptide E, also known as SNRPE, is a human gene.^[1]

[edit] References

^ Entrez Gene: SNRPE small nuclear ribonucleoprotein polypeptide E.

[edit] Further reading

Sauterer RA, Goyal A, Zieve GW (1990). "Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts.". J. Biol. Chem. 265 (2): 1048–58. PMID 1688550.
Fautsch MP, Wieben ED (1992). "Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. Identification of cis-acting sequences with homology to genes encoding ribosomal proteins.". J. Biol. Chem. 266 (34): 23288–95. PMID 1835977.
Neiswanger K, Stanford DR, Sparkes RS, et al. (1990). "Assignment of the gene for the small nuclear ribonucleoprotein E (SNRPE) to human chromosome 1q25-q43.". Genomics 7 (4): 503–8. PMID 2143747.
Stanford DR, Rohleder A, Neiswanger K, Wieben ED (1987). "DNA sequence of a human Sm autoimmune antigen. The multigene family contains a processed pseudogene.". J. Biol. Chem. 262 (21): 9931–4. PMID 2440864.
Feeney RJ, Sauterer RA, Feeney JL, Zieve GW (1989). "Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles.". J. Biol. Chem. 264 (10): 5776–83. PMID 2522439.
Stanford DR, Perry CA, Holicky EL, et al. (1988). "The small nuclear ribonucleoprotein E protein gene contains four introns and has upstream similarities to genes for ribosomal proteins.". J. Biol. Chem. 263 (33): 17772–9. PMID 2972723.
Stanford DR, Kehl M, Perry CA, et al. (1989). "The complete primary structure of the human snRNP E protein.". Nucleic Acids Res. 16 (22): 10593–605. PMID 2974536.
Woppmann A, Rinke J, Lührmann R (1989). "Direct cross-linking of snRNP proteins F and 70K to snRNAs by ultra-violet radiation in situ.". Nucleic Acids Res. 16 (23): 10985–1004. PMID 2974540.
Kamiyama T, Aoki N, Yuasa Y (1993). "B-raf oncogene: activation by rearrangements and assignment to human chromosome 7.". Jpn. J. Cancer Res. 84 (3): 250–6. PMID 8098025.
Plessel G, Lührmann R, Kastner B (1997). "Electron microscopy of assembly intermediates of the snRNP core: morphological similarities between the RNA-free (E.F.G) protein heteromer and the intact snRNP core.". J. Mol. Biol. 265 (2): 87–94. doi:10.1006/jmbi.1996.0713. PMID 9020971.
Liu Q, Fischer U, Wang F, Dreyfuss G (1997). "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins.". Cell 90 (6): 1013–21. PMID 9323129.
Fury MG, Zhang W, Christodoulopoulos I, Zieve GW (1998). "Multiple protein: protein interactions between the snRNP common core proteins.". Exp. Cell Res. 237 (1): 63–9. doi:10.1006/excr.1997.3750. PMID 9417867.
Kambach C, Walke S, Young R, et al. (1999). "Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.". Cell 96 (3): 375–87. PMID 10025403.
Charroux B, Pellizzoni L, Perkinson RA, et al. (2000). "Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems.". J. Cell Biol. 147 (6): 1181–94. PMID 10601333.
Charroux B, Pellizzoni L, Perkinson RA, et al. (2000). "Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli.". J. Cell Biol. 148 (6): 1177–86. PMID 10725331.
Urlaub H, Raker VA, Kostka S, Lührmann R (2001). "Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure.". EMBO J. 20 (1-2): 187–96. doi:10.1093/emboj/20.1.187. PMID 11226169.
Gubitz AK, Mourelatos Z, Abel L, et al. (2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins.". J. Biol. Chem. 277 (7): 5631–6. doi:10.1074/jbc.M109448200. PMID 11714716.
Pellizzoni L, Baccon J, Rappsilber J, et al. (2002). "Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component.". J. Biol. Chem. 277 (9): 7540–5. doi:10.1074/jbc.M110141200. PMID 11748230.
Friesen WJ, Wyce A, Paushkin S, et al. (2002). "A novel WD repeat protein component of the methylosome binds Sm proteins.". J. Biol. Chem. 277 (10): 8243–7. doi:10.1074/jbc.M109984200. PMID 11756452.
Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.". RNA 8 (4): 426–39. PMID 11991638.