Slow reacting substance of anaphylaxis

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LTC4
LTC4
LTD4
LTD4
LTE4
LTE4

The Slow reacting substance of anaphylaxis or SRS-A is a mixture of the leukotrienes LTC4, LTD4 and LTE4. Mast cells secrete it during the anaphylactic reaction, inducing inflammation. [1] It can be found in basophils.

It induced prolonged, slow contraction of smooth muscle and has a major bronchoconstrictor role in asthma.[2]

[edit] References

  1. ^ Dorland's Medical Dictionary. Retrieved on December 15, 2006.
  2. ^ Howard R. Morris, Graham W. Taylor, Priscilla J. Piper, John R. Tippins. Structure of slow-reacting substance of anaphylaxis from guinea-pig lung. Retrieved on December 15, 2006.

[edit] External links

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Autacoids, unsaturated fatty acids: Eicosanoids
Prostanoids
Leukotrienes
A4 - B4 - Slow reacting substance of anaphylaxis (C4, D4, E4)
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