SLC2A4RG

From Wikipedia, the free encyclopedia

SLC2A4 regulator

Identifiers

SLC2A4RG; GEF; HDBP1; Si-1-2; Si-1-2-19

External IDs

Gene ontology
Molecular Function:	• transcription factor activity • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• transcription • regulation of transcription, DNA-dependent

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

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Refseq

NM_020062 (mRNA)
NP_064446 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 20: 61.84 - 61.85 Mb

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Pubmed search

[1]

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SLC2A4 regulator, also known as SLC2A4RG, is a human gene.^[1]

The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.^[1]

[edit] References

^ ^a ^b Entrez Gene: SLC2A4RG SLC2A4 regulator.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.
Oshel KM, Knight JB, Cao KT, et al. (2000). "Identification of a 30-base pair regulatory element and novel DNA binding protein that regulates the human GLUT4 promoter in transgenic mice.". J. Biol. Chem. 275 (31): 23666–73. doi:10.1074/jbc.M001452200. PMID 10825161.
Xu XR, Huang J, Xu ZG, et al. (2002). "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver.". Proc. Natl. Acad. Sci. U.S.A. 98 (26): 15089–94. doi:10.1073/pnas.241522398. PMID 11752456.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Tanaka K, Shouguchi-Miyata J, Miyamoto N, Ikeda JE (2004). "Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene.". J. Biol. Chem. 279 (8): 7275–86. doi:10.1074/jbc.M310726200. PMID 14625278.
Knight JB, Eyster CA, Griesel BA, Olson AL (2004). "Regulation of the human GLUT4 gene promoter: interaction between a transcriptional activator and myocyte enhancer factor 2A.". Proc. Natl. Acad. Sci. U.S.A. 100 (25): 14725–30. doi:10.1073/pnas.2432756100. PMID 14630949.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
McGee SL, Sparling D, Olson AL, Hargreaves M (2006). "Exercise increases MEF2- and GEF DNA-binding activity in human skeletal muscle.". FASEB J. 20 (2): 348–9. doi:10.1096/fj.05-4671fje. PMID 16368714.