Sinapinic acid
From Wikipedia, the free encyclopedia
| Sinapinic acid | |
|---|---|
 |
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| IUPAC name | 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid |
| Other names | Sinapinic acid Sinapic acid 3,5-Dimethoxy-4-hydroxycinnamic acid 4-Hydroxy-3,5-dimethoxycinnamic acid |
| Identifiers | |
| CAS number | [530-59-6] |
| SMILES | COC1=CC(=CC(=C1O)OC)C=CC(=O)O |
| Properties | |
| Molecular formula | C11H12O5 |
| Molar mass | 224.21 g/mol |
| Melting point |
203-205 °C (decomposes) |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Sinapinic acid, or sinapic acid, is a small naturally occurring carboxylic acid. It is a member of the phenylpropanoid family. It is a commonly used matrix in MALDI mass spectrometry.[1][2] It is a useful matrix for a wide variety of peptides and proteins. It serves well as a matrix for MALDI due to its ability to absorb laser radiation and to also donate protons (H+)to the analyte of interest.
[edit] Sources
[edit] See also
Matrix-assisted laser desorption/ionization
[edit] References
- ^ Beavis RC, Chait BT (1989). "Matrix-assisted laser-desorption mass spectrometry using 355 nm radiation". Rapid Commun. Mass Spectrom. 3 (12): 436–9. doi:. PMID 2520224.
- ^ Beavis RC, Chait BT (1989). "Cinnamic acid derivatives as matrices for ultraviolet laser desorption mass spectrometry of proteins". Rapid Commun. Mass Spectrom. 3 (12): 432–5. doi:. PMID 2520223.
