SHC2

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SHC (Src homology 2 domain containing) transforming protein 2
Identifiers
Symbol(s) SHC2; SCK; SHCB; SLI
External IDs OMIM: 605217 MGI: 106180 HomoloGene: 19127
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 25759 216148
Ensembl ENSG00000129946 ENSMUSG00000020312
Uniprot P98077 Q8BMC3
Refseq XM_001129272 (mRNA)
XP_001129272 (protein)		 XM_125779 (mRNA)
XP_125779 (protein)
Location Chr 19: 0.37 - 0.41 Mb Chr 10: 79.02 - 79.04 Mb
Pubmed search [1] [2]

SHC (Src homology 2 domain containing) transforming protein 2, also known as SHC2, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: SHC2 SHC (Src homology 2 domain containing) transforming protein 2.

[edit] Further reading

  • Choy KW, Wang CC, Ogura A, et al. (2007). "Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes.". Physiol. Genomics 25 (1): 9–15. doi:10.1152/physiolgenomics.00121.2005. PMID 16368877. 
  • Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Liu HY, Meakin SO (2002). "ShcB and ShcC activation by the Trk family of receptor tyrosine kinases.". J. Biol. Chem. 277 (29): 26046–56. doi:10.1074/jbc.M111659200. PMID 12006576. 
  • Warner AJ, Lopez-Dee J, Knight EL, et al. (2001). "The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells.". Biochem. J. 347 (Pt 2): 501–9. PMID 10749680. 
  • Nakamura T, Muraoka S, Sanokawa R, Mori N (1998). "N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling.". J. Biol. Chem. 273 (12): 6960–7. PMID 9507002. 
  • Pelicci G, Dente L, De Giuseppe A, et al. (1996). "A family of Shc related proteins with conserved PTB, CH1 and SH2 regions.". Oncogene 13 (3): 633–41. PMID 8760305. 
  • Kavanaugh WM, Williams LT (1995). "An alternative to SH2 domains for binding tyrosine-phosphorylated proteins.". Science 266 (5192): 1862–5. PMID 7527937. 
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