SFRS3

From Wikipedia, the free encyclopedia

Splicing factor, arginine/serine-rich 3

Identifiers

External IDs

OMIM: 603364 MGI: 98285 HomoloGene: 55708

Gene ontology
Molecular Function:	• nucleotide binding • RNA binding • protein binding
Cellular Component:	• nucleus
Biological Process:	• mRNA processing • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003017 (mRNA)
NP_003008 (protein)

XM_991475 (mRNA)
XP_996569 (protein)

Location

Chr 6: 36.67 - 36.68 Mb

Chr 17: 28.76 - 28.77 Mb

Pubmed search

[1]

[2]

Splicing factor, arginine/serine-rich 3, also known as SFRS3, is a human gene.^[1]

[edit] References

^ Entrez Gene: SFRS3 splicing factor, arginine/serine-rich 3.

[edit] Further reading

Zahler AM, Lane WS, Stolk JA, Roth MB (1992). "SR proteins: a conserved family of pre-mRNA splicing factors.". Genes Dev. 6 (5): 837–47. PMID 1577277.
Ayane M, Preuss U, Köhler G, Nielsen PJ (1991). "A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs.". Nucleic Acids Res. 19 (6): 1273–8. PMID 2030943.
Gui JF, Lane WS, Fu XD (1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle.". Nature 369 (6482): 678–82. doi:10.1038/369678a0. PMID 8208298.
Cáceres JF, Screaton GR, Krainer AR (1998). "A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm.". Genes Dev. 12 (1): 55–66. PMID 9420331.
Zhang WJ, Wu JY (1998). "Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.". Mol. Cell. Biol. 18 (2): 676–84. PMID 9447963.
Tripodis N, Mason R, Humphray SJ, et al. (1999). "Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex.". Genome Res. 8 (6): 631–43. PMID 9647638.
Papoutsopoulou S, Nikolakaki E, Chalepakis G, et al. (1999). "SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1.". Nucleic Acids Res. 27 (14): 2972–80. PMID 10390541.
Barnard DC, Patton JG (2000). "Identification and characterization of a novel serine-arginine-rich splicing regulatory protein.". Mol. Cell. Biol. 20 (9): 3049–57. PMID 10757789.
Shnyreva M, Schullery DS, Suzuki H, et al. (2000). "Interaction of two multifunctional proteins. Heterogeneous nuclear ribonucleoprotein K and Y-box-binding protein.". J. Biol. Chem. 275 (20): 15498–503. PMID 10809782.
Elliott DJ, Bourgeois CF, Klink A, et al. (2000). "A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.". Proc. Natl. Acad. Sci. U.S.A. 97 (11): 5717–22. PMID 10823932.
Huang Y, Steitz JA (2001). "Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA.". Mol. Cell 7 (4): 899–905. PMID 11336712.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. PMID 11790298.
Barnard DC, Li J, Peng R, Patton JG (2002). "Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins.". RNA 8 (4): 526–33. PMID 11991645.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Guo TB, Boros LG, Chan KC, et al. (2003). "Spermatogenetic expression of RNA-binding motif protein 7, a protein that interacts with splicing factors.". J. Androl. 24 (2): 204–14. PMID 12634307.
Tai HH, Geisterfer M, Bell JC, et al. (2003). "CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins.". Biochem. Biophys. Res. Commun. 308 (1): 170–6. PMID 12890497.
Li J, Hawkins IC, Harvey CD, et al. (2003). "Regulation of alternative splicing by SRrp86 and its interacting proteins.". Mol. Cell. Biol. 23 (21): 7437–47. PMID 14559993.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Dettwiler S, Aringhieri C, Cardinale S, et al. (2005). "Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.". J. Biol. Chem. 279 (34): 35788–97. doi:10.1074/jbc.M403927200. PMID 15169763.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747.