Seronegative spondarthritis
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"Seronegative" refers to the fact that these diseases are negative for Rheumatoid Factor and CCP in the serum.
Seronegative spondyloarthritis is a group of diseases, including:
- psoriatic arthritis
- Reiter's disease
- arthritis in association with inflammatory bowel disease
- ankylosing spondylitis
- Behcet's syndrome
- Whipple's disease
These diseases has following conditions in common:
- They are in relation to HLA-B27
- sacroiliitis and spondylitis are present in them.
- familial aggregation occurs
- Overlap is likely in them
- rheumatoid factor is not present

